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The first examples of the directed, boron-mediated aldol reaction between different ketones are presented. Transformation of a variety of ketones to their corresponding boron enolates with Chx2BCl/Et3N, followed by reaction with acceptor ketones in diethyl ether, and oxidation of the resultant boron aldolate (H2O2, MeOH/pH 7 buffer), provided the aldol addition products. The reaction was most f...
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ژورنال
عنوان ژورنال: Justus Liebig's Annalen der Chemie
سال: 1905
ISSN: 0075-4617,1099-0690
DOI: 10.1002/jlac.19053400104